Efetividade clínica da suplementação de BCAA, L-Carnitina, Creatina, Glutamina e HMB: Um mapa de evidências

  • Georgia Muccillo Dexheimer Biomédica, Doutorado em Biotecnologia pela Universidade do Vale do Taquari-Univates, Professora da Universidade do Vale do Taquari-Univates, Lajeado-RS, Brasil.
  • Felipe Frietto de Borba Graduando em Medicina, Universidade do Vale do Taquari-Univates, Lajeado-RS, Brasil.
  • Joao Pedro Corbellini Gnoatto Graduando em Medicina, Universidade do Vale do Taquari-Univates, Lajeado-RS, Brasil.
  • Thatiane Lopes Valentim Di Pasquale Ostolin Fisioterapeuta, Mestrado Interdisciplinar em Ciências da Saúde pela Universidade Federal de São Paulo-UNIFESP; Tutora no curso de especialização em Fisiologia do Exercício Aplicada à Clínica pela UNIFESP, Santos-SP, Brasil.
Palavras-chave: Suplementos nutricionais, Hipertrofia, Exercício físico, Força muscular, Qualidade de vida

Resumo

Introdução: A hipertrofia e manutenção do tecido muscular é uma busca constante em diferentes cenários populacionais. O treinamento físico e a nutrição são fundamentais para obter tais ganhos, incluindo a suplementação. Objetivo: avaliar os efeitos da suplementação com BCAA ou aminoácidos essenciais, Creatina, L-Carnitina, Glutamina e HMB no ganho de massa muscular, força e performance em diferentes condições e grupos populacionais. Materiais e métodos: busca de artigos nas bases de dados PubMed e Biblioteca Virtual em Saúde, incluindo artigos de revisão sistemática. Foram obtidos dados das intervenções realizadas, possíveis desfechos (massa muscular, força e performance) e dados da população. Resultados: Foram incluídos 48 artigos. A população avaliada foi composta predominantemente por adultos e idosos de ambos os sexos, abordando quadros de sarcopenia, doenças crônicas ou indivíduos hígidos. A intervenção com suplementação foi combinada ou isolada, sendo associada ou não com atividade física. Os desfechos foram ganho de massa muscular, força ou resistência/performance. Em relação ao aumento de massa muscular, foram identificadas 57 intervenções diferentes com 43 casos (75%) associados a efeito positivo ou potencialmente positivo. Ainda, 39 intervenções avaliaram força e resistência muscular, sendo que 29 apresentaram efeitos positivos ou potencialmente positivos (74%). Conclusão:  Definir efeitos, dose, combinação de suplementos é importante para cada grupo populacional. Destaca-se uma necessidade de melhor definição da população avaliada, através da análise do perfil inflamatório dos indivíduos, microbiota intestinal, taxa de metabolismo basal em repouso, força máxima e VO2 máximo, níveis hormonais, etnias, comorbidades, hábitos alimentares, histórico de atividade física, entre outros.

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Publicado
2024-02-22
Como Citar
Dexheimer, G. M., Borba, F. F. de, Gnoatto, J. P. C., & Ostolin, T. L. V. D. P. (2024). Efetividade clínica da suplementação de BCAA, L-Carnitina, Creatina, Glutamina e HMB: Um mapa de evidências. RBNE - Revista Brasileira De Nutrição Esportiva, 18(108), 111-134. Recuperado de https://www.rbne.com.br/index.php/rbne/article/view/2250
Edição
v. 18 n. 108 (2024)
Seção
Artigos Científicos - Revisão

Copyright (c) 2024 Georgia Muccillo Dexheimer, Felipe Frietto de Borba, Joao Pedro Corbellini Gnoatto, Thatiane Lopes Valentim Di Pasquale Ostolin

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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