Relationship of β-alanine supplementation on carnosine concentration in anaerobic and aerobic exercises: a systematic review
Abstract
Carnosine has a significant role in the regulation of muscle pH, being considered a factor of neuromuscular strengthening of physical capabilities and reduction of muscle fatigue. However, this substance is dependent on the supplementation with β-alanine for its synthesis, and in this case, the use of β-alanine can be considered an excellent ergogenic aid for sports performance. Therefore, this study aimed to perform a systematic review on the effect of β-alanine supplementation on physical performance in anaerobic and aerobic exercises. To conduct this study, we searched for articles indexed in PubMed, BVS, and Science Direct databases, selected from the Medical Subject Heading (MeSH) and Health Science Descriptors (DeCS): β-alanine AND Physical Exercise OR Physical Performance. Eleven articles were selected covering 215 people who received between 5 and 12 g of β-alanine/day during an interval of 2 to 24 weeks. Increased intramuscular carnosine and improved physical performance data in modalities after supplementation were observed. Therefore, although factors such as age, gender, and skeletal muscle fiber type influence intramuscular carnosine levels, the analysis of β-alanine supplementation protocols at different intervals and doses proved effective in increasing intramuscular carnosine levels, especially in high-intensity aerobic exercise.
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Copyright (c) 2023 Mabel Quereno de Oliveira Luna Siebra de Freitas, Milfont Milfont, Kamila Alves da Silva, Francisca Letícia de Oliveira Lima, Francisco Fábio Bezerra de Oliveira, Ana Cibele Pereira Sousa Sousa, Stéfany Rodrigues de Sousa Melo
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