The mannering standard of rats supplemented with amino acid leucine
Abstract
Supplementation with branched chain amino acids has been disseminated widely among practitioners of physical activities. Studies suggest the development of central fatigue during activity, its correlation brain serotonin and leucine. Purpose of this study was to evaluate through tests of open field and elevated plus-maze, the behavior of rats supplemented with three different doses of leucine. Wistar rats were divided into groups: control (C), leucine 0.30mM/100g (L0,30), 1.25mM/100g (L1,25) and 5mM/100g (L5), supplemented via oral gavage. For statistical analysis, variance followed by Tukey test (p<0.05). The exploratory behavior was observed that rats L0,30 did not differ from C and the groups L1,25 and L5, showed a reduction. In the elevated plus-maze group C compared with L0,30 and L1,25 did not get the difference, the L5 group differed from the others. The results suggest the existenceof physiological and behavioral changes related to supplementation with leucine.
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