Evaluation of food and physical training on the memory and learning in diabetic rats
Abstract
Aim: To evaluate the influence of physical training and food restriction on learning and memory of diabetic rats. Materials and methods: Forty female Wistar rats, diabetic streptozotocin induced, were divided into 4 groups (n = 10 / group). The G1 corresponded to the control group and had free access to food and water. The G2 - Food Restriction group - received water ad libitum and feed restriction. The G3 to the swimming group that performed physical training for 10 minutes a day during the three weeks of the experiment. The G4 referred to the group Food Restriction + Swimming, which was submitted to the same methodological procedures of G2 and G3. In the twenty-first day the groups were evaluated in Inhibitory Dodge comparing the data by ANOVA followed by Tukey test. Results: The data showed a significant increase (p <0.01) in the time spent on the platform of the G2 group. For animals of G1, G3 and G4, although the platform length of stay was higher in the test session, the difference was not significant. Conclusions: The results of this study and according to the methodology used indicate that in diabetic animals, moderate food restriction (30%) improved performance on the learning and memory compared to the control animals and rats of swimming groups.
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