Influence of the dose and protein distribution on muscle protein synthesis, associated or not to resistance training sessions
Abstract
It is well known that the main stimuli for the gain of muscle mass are exercise and protein intake. For decades, researchers of the field of sports nutrition, have been studying how to get the most between these stimuli on the muscle mass gain. Nowadays, there are vast scientific works highlighting some nutritional factors which might influence the response of the muscle protein synthesis (MPS) as well as muscle protein degradation (MPD) on muscle gain. Among those factors, it is included the protein dose and the protein distribution along the day, yet controversial. Then, the aim of this narrative review was to summarize the studies that have investigated the influence of the dose and protein distribution, associated or not, to resistance training sessions, on MPS. A narrative literature review was performed using the PubMed database. Among 16 articles found, ten of them were selected for analysis. Between them, seven original articles were selected for discussing the influence of the protein dose on MPS and another three were analyzed for discussing the influence of protein distribution on protein synthesis. Despite of existing fascinating articles about this topic, it is still too soon to conclude that by manipulating these strategies - protein dose and protein distribution -, would guarantee a superior muscle gain in long term. However, it is still interesting that young men reach at least 20 grams of protein during their main meals at regular intervals, every three hours
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