Variations in haematological parameters in obese, sedentary, aerobic-training and resistance-training populations

  • Betül Kaplan Dialisys Program, Hasan Kalyoncu University, Gaziantep, Türkiye.
  • Hakim Çelik Department of Physiology, Harran University, Sanliurfa, Turkiye.
  • Yusuf Hoşoğlu Education and Research Hospital, Adiyaman, Turkye.
  • Mehmet Küçük Department of Physiology, Harran University, Sanliurfa, Turkiye.
  • Yakup Aktaş School of Physical Education and Sports, Harran University, Sanliurfa, Turkiye.
  • Mehmet Ali Eren Department of Endocrinology, Harran University, Sanliurfa, Turkiye.

Resumo

Introduction: Although physical activity has a considerable impact on various laboratory markers, evidence on haematological alterations, cardiovascular risk factors and inflammatory mediators after resistance-training is limited. Objective: The aim of this study is to investigate alterations in hematological parameters among populations engaging in obesity, sedentary behavior, aerobic exercise, and resistance training. Materials and Methods: A study with 122 male volunteers aged 18-45 divided into four groups based on exercise type and Body Mass Index. It compared blood parameters of resistance exercisers to normal-weight sedentary, overweight/obese individuals, and normal-weight aerobic exercisers. Blood count included RBC, HCT, reticulocyte, platelet counts, hemoglobin, MCV, MCH, RDW, and MPV. Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII) were determined based on hemogram. Results: Resistance training may have negative effects on individuals at cardiovascular risk, but it was found to be advantageous for athletes or sedentary adults with a good vascular endothelium to raise HCT and, possibly, enhance tissue blood supply by inducing vasodilation.

Referências

-Brun, J.; Fons, C.; Supparo, I.; Mallard, C.; Orsetti, A. Could exercise-induced increase in blood viscosity at high shear rate be entirely explained by hematocrit and plasma viscosity changes? Clinical Hemorheology and Microcirculation. Vol. 13. Num. 2. 1993. p, 187-199.

-Cabrales, P.; Martini, J.; Intaglietta, M.; Tsai, A.G. Blood viscosity maintains microvascular conditions during normovolemic anemia independent of blood oxygen-carrying capacity. American Journal of Physiology-Heart and Circulatory Physiology. Vol. 291. Num. 2. 2006. p. H581-H590.

-Cardoso, A.; Bagatini, M.; Roth, M.; Martins, C.; Rezer, J.; Mello, F.; Schetinger, M. Acute effects of resistance exercise and intermittent intense aerobic exercise on blood cell count and oxidative stress in trained middle-aged women. Brazilian journal of medical and biological research. Num. 45. 2012. p. 1172-1182.

-Chen, J.H.; Zhai, E.T.; Yuan, Y.J.; Wu, K.M.; Xu, J.B.; Peng, J.J.; Cai, S.R. Systemic immune-inflammation index for predicting prognosis of colorectal cancer. World J Gastroenterol. Vol. 23. Num. 34. 2017. p. 6261-6272. doi: 10.3748/wjg.v23.i34.6261

-Coban, E.; Ozdogan, M.; Yazicioglu, G.; Akcit, F. The mean platelet volume in patients with obesity. International journal of clinical practice. Vol. 59. Num. 8. 2005. p. 981-982.

-Connes, P.; Sara, F.; Hardy-Dessources, M.-D.; Marlin, L.; Etienne, F.; Larifla, L.; Hue, O. Effects of short supramaximal exercise on hemorheology in sickle cell trait carriers. European journal of applied physiology. Vol. 97. Num. 2. 2006. p. 143-150.

-Connes, P.; Simmonds, M.J.; Brun, J.-F.; Baskurt, O.K. Exercise hemorheology: classical data, recent findings and unresolved issues. Clinical Hemorheology and Microcirculation. Vol. 53. Num. 1-2. 2013. p. 187-199.

-Joisten, N.; Proschinger, S.; Rademacher, A.; Schenk, A.; Bloch, W.; Warnke, C.; Zimmer, P. High-intensity interval training reduces neutrophil-to-lymphocyte ratio in persons with multiple sclerosis during inpatient rehabilitation. Multiple Sclerosis Journal. Vol. 27. Num. 7. 2021. p. 1136-1139.

-Kilic-Toprak, E.; Ardic, F.; Erken, G.; Unver-9-Kocak, F.; Kucukatay, V.; Bor-Kucukatay, M. Hemorheological responses to progressive resistance exercise training in healthy young males. Med Sci Monit. Vol. 18. Num. 6. 2012. p. Cr351-360. doi: 10.12659/msm.882878

-Kimura, T.; Hamada, H.; Taito, S.; Takahashi, M.; Sekikawa, K. The effect of exercise on blood fluidity: use of the capillary model to assess the clogginess of blood. Clinical Hemorheology and Microcirculation. Vol. 61. Num. 4. 2015. p. 559-569.

-Korkmaz, A.; Yıldız, A.; Türker Duyuler, P.; Duyuler, S.; Yılmaz, S.; Basyigit, F.; Ileri, M. Combination of change in hematological parameters with exercise stress test to predict coronary artery disease. Journal of clinical laboratory analysis. Vol. 32. Num. 1. 2018. p. e22205.

-Lamprecht, M.; Moussalli, H.; Ledinski, G.; Leschnik, B.; Schlagenhauf, A.; Koestenberger, M.; Cvirn, G. Effects of a single bout of walking exercise on blood coagulation parameters in obese women. Journal of applied physiology. Vol. 115. Num. 1. 2013. p. 57-63.

-Leite, N.R.P.; Siqueira de Medeiros, M.; Mury, W.V.; Matsuura, C.; Perszel, M.B.M.; Noronha Filho, G.; Mendes‐Ribeiro, A.C. Platelet hyperaggregability in obesity: is there a role for nitric oxide impairment and oxidative stress? Clinical and Experimental Pharmacology and Physiology. Vol. 43. Num. 8. 2016. p. 738-744.

-Li, H.; Wu, X.; Bai, Y.; Wei, W.; Li, G.; Fu, M.; Guo, H. Physical activity attenuates the associations of systemic immune-inflammation index with total and cause-specific mortality among middle-aged and older populations. Sci Rep. Vol. 11. Num. 1. 2021. p. 12532. doi: 10.1038/s41598-021-91324-x

-Madjid, M.; Awan, I.; Willerson, J.T.; Casscells, S.W. Leukocyte count and coronary heart disease: implications for risk assessment. J Am Coll Cardiol. Vol. 44. Num. 10. 2004. p. 1945-1956. doi: 10.1016/j.jacc.2004.07.056

-Makras, P.; Koukoulis, G.N.; Bourikas, G.; Papatheodorou, G.; Bedevis, K.; Menounos, P.; Kartalis, G. Effect of 4 weeks of basic military training on peripheral blood leucocytes and urinary excretion of catecholamines and cortisol. Journal of sports sciences. Vol. 23. Num. 8. 2005. p. 825-834.

-Martin, J. Platelet heterogeneity in vascular disease Platelet Heterogeneity. p. 205-226: Springer. 1990.

-Morton, R.W.; Murphy, K.T.; McKellar, S.R.; Schoenfeld, B.J.; Henselmans, M.; Helms, E.; Phillips, S.M. A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength in healthy adults. Vol. 52. Num. 6. 2018. p. 376-384. doi: 10.1136/bjsports-2017-097608

-Neuhaus, D.; Gaehtgens, P. Haemorrheology and long term exercise. Sports Medicine. Vol. 18. Num. 1. 1994. p. 10-21.

-Peake, J.M.; Neubauer, O. Recovery of the immune system after exercise. Vol. 122. Num. 5. 2017. p. 1077-1087. doi: 10.1152/japplphysiol.00622.2016

-Ranucci, M.; Aloisio, T.; Di Dedda, U.; La Rovere, M.T.; Arroyabe, B.M.L.; Baryshnikova, E. Platelet reactivity in overweight and obese patients undergoing cardiac surgery. Platelets. Vol. 30. Num. 5. 2019. p. 608-614.

-Ross, R. Atherosclerosis-an inflammatory disease. N Engl J Med. Vol. 340. Num. 2. 1999. p. 115-126. doi: 10.1056/nejm199901143400207

-Salazar Vázquez, B.Y.; Salazar Vázquez, M.A.; Jáquez, M.G.; Bracho Huemoeller, A.H.; Intaglietta, M.; Cabrales, P. Blood pressure directly correlates with blood viscosity in diabetes type 1 children but not in normals. Clinical Hemorheology and Microcirculation. Vol. 44. Num. 1. 2010. p. 55-61.

-Schlagheck, M.L.; Walzik, D.; Joisten, N.; Koliamitra, C.; Hardt, L.; Metcalfe, A.J.; Zimmer, P. Cellular immune response to acute exercise: Comparison of endurance and resistance exercise. Eur J Haematol. Vol. 105. Num. 1. 2020. p. 75-84. doi: 10.1111/ejh.13412

-Sofi, F.; Capalbo, A.; Cesari, F.; Abbate, R.; Gensini, G.F. Physical activity during leisure time and primary prevention of coronary heart disease: an updated meta-analysis of cohort studies. European Journal of Preventive Cardiology. Vol. 15. Num. 3. 2008. p. 247-257.

-Țaranu, I.; Lazea, C.; Creț, V.; Răcătăianu, N.; Iancu, M. Inflammation-Related Markers and Thyroid Function Measures in Pediatric Patients: Is the Grade of Obesity Relevant?. Vol. 11. Num. 3. 2021. doi: 10.3390/diagnostics11030485

-Temiz, A.; Başkurt, O.; Pekcetin, C.; Kandemir, F.; Güre, A. Leukocyte activation, oxidant stress and red blood cell properties after acute, exhausting exercise in rats. Clinical Hemorheology and Microcirculation. Vol. 22. Num. 4. 2000. p. 253-259.

-Tripette, J.; Hardy-Dessources, M.-D.; Beltan, E.; Sanouiller, A.; Bangou, J.; Chalabi, T.; Nebor, D. Endurance running trial in tropical environment: A blood rheological study. Clinical Hemorheology and Microcirculation. Vol. 47. Num. 4. 2011. p. 261-268.

-Varol, E.; Akcay, S.; Ozaydin, M.; Erdogan, D.; Dogan, A.; Altinbas, A. Mean platelet volume is associated with insulin resistance in non-obese, non-diabetic patients with coronary artery disease. Journal of cardiology. Vol. 56. Num. 2. 2010. p. 154-158.

-Vázquez, B.Y.S.; Cabrales, P.; Tsai, A.G.; Intaglietta, M. Nonlinear cardiovascular regulation consequent to changes in blood viscosity. Clinical Hemorheology and Microcirculation. Vol. 49. Num. 1-4. 2011. p. 29-36.

-Vilahur, G.; Ben-Aicha, S.; Badimon, L. New insights into the role of adipose tissue in thrombosis. Cardiovascular research. Vol. 113. Num. 9. 2017. p. 1046-1054.

-Wahl, P.; Mathes, S.; Bloch, W.; Zimmer, P. Acute impact of recovery on the restoration of cellular immunological homeostasis. International Journal of Sports Medicine. Vol. 41. Num. 01. 2020. p. 12-20.

-Walzik, D.; Joisten, N. Transferring clinically established immune inflammation markers into exercise physiology: focus on neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and systemic immune-inflammation index. Vol. 121. Num. 7. 2021. p. 1803-1814. doi: 10.1007/s00421-021-04668-7

-Wang, R.; Chen, P.; Chen, W. Diet and exercise improve neutrophil to lymphocyte ratio in overweight adolescents. International Journal of Sports Medicine. Vol. 32. Num. 12. 2011. p. e1-e5.

-Wyrostek, J.; Piotrowska, A.; Czerwińska-Ledwig, O.; Zuziak, R.; Szyguła, Z.; Cisoń, T.; Pilch, W. Complex effects of whole body cryostimulation on hematological markers in patients with obesity. PloS one. Vol. 16. Num. 4. 2021. p. e0249812.

-Yalcin, O.; Erman, A.; Muratli, S.; Bor-Kucukatay, M.; Baskurt, O.K. Time course of hemorheological alterations after heavy anaerobic exercise in untrained human subjects. Journal of applied physiology. Vol. 94. Num. 3. 2003. p. 997-1002.

Publicado
2024-12-11
Como Citar
Kaplan, B., Çelik, H., Hoşoğlu, Y., Küçük, M., Aktaş, Y., & Eren, M. A. (2024). Variations in haematological parameters in obese, sedentary, aerobic-training and resistance-training populations. RBNE - Revista Brasileira De Nutrição Esportiva, 18(112), 447-455. Obtido de https://www.rbne.com.br/index.php/rbne/article/view/2325
Secção
Artigos Científicos - Original